Optimization of Pharmaceutical R&D Programs and Portfolios

Need for Optimal Design of Pharmaceutical Programs and Portfolios in Modern Medical Product Development.- Clinical Aspects of Pharmaceutical Portfolio Management.- Drug Development and the Cost of Capital.- Investment Considerations for Pharmaceutical Product Portfolios.- Challenges of Portfolio Management in Pharmaceutical Development.- Impact of Phase 2b Strategies on Optimization of Drug Development Programs.- Using Decision Analysis to Support the Design of Clinical Trials at a Program Level.- Indication Sequencing for a New Molecular Entity with Multiple Potential Oncology Indications.- Maximizing Return on Investment in Phase II Proof-of-Concept Trials.- Portfolio Optimization of Therapies and Their Predictive Biomarkers.- Dynamically Optimizing Budget Allocation for Phase 3 Drug Development Portfolios Incorporating Uncertainty in the Pipeline.

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• Pesquisa operacional
• Optimização
• Decisões de gestão
• Probabilidade e Estatística

Decision Analysis;Decision Making;Optimization;Pharmaceutical Portfolio;Portfolio Optimization;Quantitative Methods