Phylogenomics
-15%
portes grátis
Phylogenomics
An Introduction
Bleidorn, Christoph
Springer International Publishing AG
08/2018
222
Mole
Inglês
9783319853079
15 a 20 dias
496
Descrição não disponível.
1. Genomes.- 01.1 Prokaryotes vs. Eukaryotes.- 01.2 Genome Structure.- 01.3 Genome Sizes.- 01.4 Human Genome and Ancient DNA (Neandertaler, Denisova).- 2. Genomes of Organelles.- 02.1 Mitochondria.- 02.2 Plastids.- 02.3 Outlook Obligate Endosymbionts.- 3. Transcriptomes.- 03.1 mRNA.- 03.2 Transcripts.- 03.3 Expression Level.- 03.4 Alternative Splicing.- 4. Sequencing Techniques.- 04.1 Sanger.- 04.2 Illumina.- 04.3 454.- 04.4 PacBio.- 04.5 Outlook Nanopore Sequencing.- 5. Genome Sequencing Strategies.- 05.1 Whole Genome Shotgun.- 05.2 RADseq.- 05.3 Target Enrichment.- 05.4 RNAseq.- 6. Assembly and Mapping.- 06.1 Assembling Strategies (kmer vs OLC).- 06.2 Data Quality and Filtering.- 06.3 Re-Sequencing and Mapping.- 06.4 De novo Assembly Genome.- 06.5 De novo Assembly Transcriptome.- 7. Locating Genes.- 07.1 Orthology vs. Paralogy.- 07.2 BLAST and Successors.- 07.3 Hidden Markov Profile.- 07.4 Ortholog Conjecture.- 8. Alignment.- 08.1 Alignment Strategies.- 08.2 Alignment Masking.- 9. Phylogenetic Analysis.- 09.1 Distance Measurements.- 09.2 Maximum Parsimony.- 09.3 Maximum Likelihood.- 09.4 Bayesian Inference.- 09.5 Supermatrix vs. Single Gene Analysis (Gene Trees vs. Species Trees).- 10. Systematic Errors in phylogenetic Analysis.- 10.1 Prediction: Evolutionary Models.- 10.2 Heterogenity Nucleotide/Amino Acid-Composition.- 10.3 Variation of substitution rate between the lines.- 10.4 Variation of substitution rate over time.- 10.5 New Approaches to Correct systematic Errors.- 11. Genome-wide Characteristics.- 11.1 Gene Order.- 11.2 Mobile Elements.- 11.3 microRNAs.- 11.4 Differences in the genetic code.- 12. Index.- 13. References
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comparative genetics;evolutionary genomics;gene expression;genome sequencing;homology research;phylogenetic analysis
1. Genomes.- 01.1 Prokaryotes vs. Eukaryotes.- 01.2 Genome Structure.- 01.3 Genome Sizes.- 01.4 Human Genome and Ancient DNA (Neandertaler, Denisova).- 2. Genomes of Organelles.- 02.1 Mitochondria.- 02.2 Plastids.- 02.3 Outlook Obligate Endosymbionts.- 3. Transcriptomes.- 03.1 mRNA.- 03.2 Transcripts.- 03.3 Expression Level.- 03.4 Alternative Splicing.- 4. Sequencing Techniques.- 04.1 Sanger.- 04.2 Illumina.- 04.3 454.- 04.4 PacBio.- 04.5 Outlook Nanopore Sequencing.- 5. Genome Sequencing Strategies.- 05.1 Whole Genome Shotgun.- 05.2 RADseq.- 05.3 Target Enrichment.- 05.4 RNAseq.- 6. Assembly and Mapping.- 06.1 Assembling Strategies (kmer vs OLC).- 06.2 Data Quality and Filtering.- 06.3 Re-Sequencing and Mapping.- 06.4 De novo Assembly Genome.- 06.5 De novo Assembly Transcriptome.- 7. Locating Genes.- 07.1 Orthology vs. Paralogy.- 07.2 BLAST and Successors.- 07.3 Hidden Markov Profile.- 07.4 Ortholog Conjecture.- 8. Alignment.- 08.1 Alignment Strategies.- 08.2 Alignment Masking.- 9. Phylogenetic Analysis.- 09.1 Distance Measurements.- 09.2 Maximum Parsimony.- 09.3 Maximum Likelihood.- 09.4 Bayesian Inference.- 09.5 Supermatrix vs. Single Gene Analysis (Gene Trees vs. Species Trees).- 10. Systematic Errors in phylogenetic Analysis.- 10.1 Prediction: Evolutionary Models.- 10.2 Heterogenity Nucleotide/Amino Acid-Composition.- 10.3 Variation of substitution rate between the lines.- 10.4 Variation of substitution rate over time.- 10.5 New Approaches to Correct systematic Errors.- 11. Genome-wide Characteristics.- 11.1 Gene Order.- 11.2 Mobile Elements.- 11.3 microRNAs.- 11.4 Differences in the genetic code.- 12. Index.- 13. References
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
