D-type Cyclins and Cancer

D-type Cyclins and Cancer

Hinds, Philip W.; Brown, Nelson E.

Birkhauser Verlag AG

10/2017

152

Dura

Inglês

9783319644493

15 a 20 dias

3731

Descrição não disponível.
The D-type Cyclins: A Historical Perspective.- Mammalian Development and Cancer - A Brief History of Mice Lacking D-type Cyclins or Cdk4/6.- D-type Cyclins and Gene Transcription.- Splice Variants and Phosphorylated Isoforms of Cyclin D1 in Tumorigenesis.- Cyclin D1, Metabolism, and the Autophagy-Senescence Balance.- Shifting a Paradigm: Cyclin D Activates pRb by Mono-Phosphorylation.
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D1-S transition;cyclin protein;human tumors;oncogenes;tumorigenesis;Cell Cycle Analysis