Collagen Mimetic Peptides and Their Biophysical Characterization

Introduction to collagen.- Structure of collagen triple helix.- Bioinformatics-aided Design of collagen mimic peptides.- Synthesis of collagen peptides.- CD characterization of triple helix stability.- Structural insights from X-ray crystallography.- Conformational and dynamic characterization by NMR spectroscopy.- Fluorescence detection of collagen biomarkers.- Synthesis and characterization of heterotrimeric models of collagen.- Self-assembly of collagen mimic peptides.- Concluding remarks.

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• Biofísica
• Proteinas
• Ciência dos materiais

Biomimetic peptide;Triple helix;Collagen;Protein structure;Protein dynamics;Biophysics characterization;X-ray fluorescence;Nuclear magnetic resonance;NMR spectroscopy;Circular dichroism spectrum