Understanding Depression

Understanding Depression

Volume 1. Biomedical and Neurobiological Background

Kim, Yong-Ku

Springer Verlag, Singapore

01/2018

322

Dura

Inglês

9789811065798

15 a 20 dias

1096


ebook

Descrição não disponível.
1.Genetic and epigenetic aspects of depression.- 1-1.Highlights on pharmacogenetics and pharmacogenomics in depression.- 1-2.Imaging genetics studies on susceptibility genes for major depressive disorder: the present and the future.- 1-3.Gene-environmental interaction and role of epigenetic in depression.- 1-4.The role of microRNAs and long noncoding RNAs in depression: diagnosis and therapeutic implication.- 1-5.The role of early life stress in HPA axis and depression.- 2.Molecular-, cellular-level aspects of depression.- 2-1.Complex role of serotonin receptors in depression.- 2-2.Emerging role of glutamate receptors in pathophysiology of depression.- 2-3.New perspective on mTOR pathways: a new target of depression.- 2-4.Cellular aging in depression: the role of telomere-telomerase system.- 2-5.Differentiation and biological markers in subtype of depression.- 3.Neural circuit-level aspect of depression.- 3-1.Molecular, structural, and functional neuroimaging in depression.- 3-2.Resting-state activity in depression; a link to spatiotemporal psychopathology.- 3-3.Functional neuroimaging in depression: a tool to predict treatment outcome and response.- 3-4.Cortical-subcortical interactions in the pathophysiology of depression.- 3-5.Pathophysiology and treatment strategies for different types of depression.- 3-6.The effect of neurostimulation in depression.- 4.Multicellular system-level aspect of depression.- 4-1.Inflammation, depression and neurodegeneration: a possible cause of dementia in late life depression?.- 4-2.Gut-microbiota-brain axis and depression.- 4-3.The interactions of immune inflammation and oxidative and nitrosative stress with the kynurenine and melatonergic pathways in depression.- 4-4.Glia-neuron cross-talk in depression.- 4-5.Depression model in primate: relevance to novel drug discovery.- 5.Species-, individual-, gender-, culture-specific aspects of depression.- 5-1.Precision psychiatry: personalized clinical approach to depression.- 5-2.Gender differences in depression.- 5-3.An up-date on the epidemiology of major depressive disorder across cultures.
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Pharmacogenetics;Imaging genetics;Early life stress;Seretonin receptors;Glutamate receptors;mTOR pathway;Cellular aging;Biological markers;Neuroimaging;Cortical-subcortical interactions;Novel drug discovery;Personalized clinical approach;Gender differences;Epidemiology of major depressive disorder