Polymer Nanoparticles for Nanomedicines

Polymer Nanoparticles for Nanomedicines

A Guide for their Design, Preparation and Development

Ponchel, Gilles; Vauthier, Christine

Springer International Publishing AG

07/2018

641

Mole

Inglês

9783319823492

15 a 20 dias

1015

Descrição não disponível.
Preface.- Introduction Part I: Polymer nanoparticles for in vivo applications: Progress on preparation methods and future challenges.- Nanoprecipitation process: From particlepreparation to in vivo applications.- Targeted Theragnostic Nanoparticles via Flash Nanoprecipitation: Principles of Materials Selection.- Preparation of polymer nanoparticles by the emulsification-solvent evaporation method: from Vanderhoff?s pioneer approach to recent adaptations.- Methods for the preparation of nanoparticles by polymerization.- Shape-controlled nanoparticles for drug delivery and targeting applications.- Physicochemical characterization of polymer nanoparticles: Challenges and present limitations.- Imaging polymer nanoparticles by means of transmission and scanning electron microscopy techniques.- Evaluating the interactions between proteins and components of the immune system with polymer nanoparticles.- Investigating interactions between nanoparticles and cells: internalization and intracellular trafficking.- Characterization of mucoadhesive interactions between nanoparticles and epithelial membranes.- Designing polymer nanoparticle nanomedicines: potential applications and challenges.- Selecting and designing polymers suitable for nanoparticles manufacturing.- Associating Drugs with Polymer Nanoparticles: A Challenge.- Drug delivery by nanoparticles: The Challenge of Controlled Release and Evaluation.- Interaction between nanoparticles and plasma proteins: effects on nanoparticle biodistribution and toxicity.- Toxicological aspects of polymer nanoparticles.- Theranostics: In Vivo.- Nanomedicines -A scientific toy or an emerging market?.- Regulatory perspective on the development of polymeric nanomaterials.
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theranostics;nanoprecipitation;drug delivery;anticancer agents;encapsulation;immune system;Proteomics