Organelle Contact Sites

Organelle Contact Sites

From Molecular Mechanism to Disease

Simmen, Thomas; Tagaya, Mitsuo

Springer Verlag, Singapore

09/2017

257

Dura

Inglês

9789811045660

15 a 20 dias

6501

Descrição não disponível.
Part 1: Overview of Organelle Contacts.- Chapter 1: Organelle Communication at Membrane Contact Sites (MCS): From Curiosity to Center Stage in Cell Biology and Biomedical Research.- Part 2: Organization and Roles of Organelle Contact Sites.- Chapter 2: Over Six Decades of Discovery and Characterization of the Architecture at Mitochondria-Associated Membranes (MAMs).- Chapter 3: Regulation of mitochondrial dynamics and autophagy by the mitochondria-associated membrane.- Chapter 4: Endoplasmic Reticulum-Mitochondria Communication Through Ca2+ signaling: the importance of mitochondria associated membranes (MAMs).- Chapter 5: Ceramide transport from the endoplasmic reticulum to the trans Golgi region at organelle membrane contact sites.- Chapter 6: Endoplasmic Reticulum - Plasma Membrane cross-talk mediated by the extended synaptotagmins.- Chapter 7: Endoplasmic Reticulum-Plasma membrane contacts regulate cellular excitability.- Chapter 8: The lipid droplet and the endoplasmic reticulum.- Chapter 9: Role of intra- and inter-mitochondrial membrane contact sites in yeast phospholipid biogenesis.- Chapter 10: Discovery and roles of ER-endolysosomal contact sites in disease.- Part 3: Infection and Disease.- Chapter 11: Alzheimer disease.- Chapter 12: Mitochondrial-associated membranes in Parkinson's disease.- Chapter 13: Role of endoplasmic reticulum-mitochondria communication in type 2 diabetes.- Chapter 14: Mitochondria-endoplasmic reticulum contact sites mediate innate immune responses.- Chapter 15: Hepatitis C Virus Replication.- Chapter 16: Hijacking of Membrane Contact Sites by Intracellular Bacterial Pathogens.- Chapter 17: Alterations in Ca2+ signalling via ER-mitochondria contact site remodelling in cancer.
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Mitochondria;Mitochondria-associated membrane;Membrane contact sites;Endoplasmic reticulum;Alzheimer's disease;Parkinson's disease;Type II diabetes;Hepatitis C virus;Cancer;Lipid synthesis;Apoptosis;Calcium;Neurodegenerative disease;Pathogen infection