Damage-Associated Molecular Patterns in Human Diseases
-15%
portes grátis
Damage-Associated Molecular Patterns in Human Diseases
Volume 1: Injury-Induced Innate Immune Responses
Land, Walter Gottlieb
Springer International Publishing AG
10/2018
870
Dura
Inglês
9783319786544
15 a 20 dias
1966
Descrição não disponível.
Part I. The Three Major Paradigms in Modern Immunology.- Prologue: The Term "Immunity" over the Course of Time.- The Three Major Paradigms in Immunology.- Epilogue: What Major Paradigm in Immunology Comes Next?.- Part II. The Innate Immune System: an Organ of Perception Determined to Maintain Homeostasis.- Prologue: The Guardians of Homeostasis.- Innate Immune Recognition Molecules.- Epilogue: The Innate Immune System: a Global Player in Health and Disease.- Part III. The Whole Family of Mammalian Innate Immune Cells.- Prologue: The Whole Body as an Immune System?.- Mobile Innate Immune Cells.- Sessile Innate Immune Cells.- Epilogue: The Whole Body as an Immune Defence System.- Part IV. The World of DAMPs. Prologue: About DAMPs, PAMPs and MAMPs.- Endogenous DAMPs, Category I: Constitutively Expressed Native Molecules (Cat. I DAMPs).- Endogenous DAMPs, Category II: Constitutively Expressed, Injury-Modified Molecules (Cat. II DAMPs).- Endogenous DAMPs, Category III: Inducible DAMPs (Cat. III DAMPs).- Exogenous DAMPs, Category IV (Cat. IV DAMPs).- Epilogue: The Well-Dosed Work of DAMPs in their Commission to Restore and Maintain Homeostasis.- Part V. Cellular Stress Responses and Regulated Cell Death.- Prologue: Innate Immune Tools to Defend against Stressful Injury: Success and Failure.- Cell-Autonomous (Cell-Intrinsic) Stress Responses.- Regulated Cell Death.- Epilogue: The Horror of an Injury-Induced Avalanche of DAMPs.- Part VI. Innate Immune Effector Responses.- Prologue: The Various Facets of Innate Immune Effector Responses.- Cellular Inflammatory Responses.- Humoral Innate Immune Effector Responses.- Regulation of Innate Inflammatory Responses.- Epilogue to Part VI.- Part VII. Function of Innate Lymphoid Cells and Unconventional T Cells with Partial Innate Function.- Prologue: The "Ready-to-Go" Lymphocytes of the Immune System.- Activating and Function of Innate Lymphoid Cells.- Activating and Function of Unconventional T Cells.- Epilogue: Killer Lymphocytes as Tools for Future Immunotherapeutic Approaches.- Part VIII. DAMPs Promoting Adaptive Immunity and Tissue Repair.- Prologue: The "Long Arm" of DAMPs in Shaping Adaptive Immune Responses and Tissue Repairing Processes.- Antigen Uptake, Processing and Presentation by Dendritic Cells.- Antigen in the Presence of DAMPs Induces Immunostimulatory Dendritic Cells to Promote "Destructive" Acquired Immune Responses.- Antigen in the Absence of DAMPs Promotes Immunotolerance: the Role of Dendritic Cells and Regulatory T Cells.- An Impressive Example of Peripheral Tolerance against Nonself: Tolerance to Commensal Bacterial and Dietary Protein Antigens.- Immunometabolism of Dendritic Cells and T Cells.- Role of DAMPs in Tissue Regeneration and Repair.- Epilogue: DAMPs as Key Players in the Pathogenesis of Many Human Diseases.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
innate immunity;damage-associated molecular patterns;autoimmune diseases;metabolic diseases;traumatic diseases;allergic diseases;cardiovascular diseases;neurodegenerative diseases;malignant diseases;cellular stress responses;translational medicine
Part I. The Three Major Paradigms in Modern Immunology.- Prologue: The Term "Immunity" over the Course of Time.- The Three Major Paradigms in Immunology.- Epilogue: What Major Paradigm in Immunology Comes Next?.- Part II. The Innate Immune System: an Organ of Perception Determined to Maintain Homeostasis.- Prologue: The Guardians of Homeostasis.- Innate Immune Recognition Molecules.- Epilogue: The Innate Immune System: a Global Player in Health and Disease.- Part III. The Whole Family of Mammalian Innate Immune Cells.- Prologue: The Whole Body as an Immune System?.- Mobile Innate Immune Cells.- Sessile Innate Immune Cells.- Epilogue: The Whole Body as an Immune Defence System.- Part IV. The World of DAMPs. Prologue: About DAMPs, PAMPs and MAMPs.- Endogenous DAMPs, Category I: Constitutively Expressed Native Molecules (Cat. I DAMPs).- Endogenous DAMPs, Category II: Constitutively Expressed, Injury-Modified Molecules (Cat. II DAMPs).- Endogenous DAMPs, Category III: Inducible DAMPs (Cat. III DAMPs).- Exogenous DAMPs, Category IV (Cat. IV DAMPs).- Epilogue: The Well-Dosed Work of DAMPs in their Commission to Restore and Maintain Homeostasis.- Part V. Cellular Stress Responses and Regulated Cell Death.- Prologue: Innate Immune Tools to Defend against Stressful Injury: Success and Failure.- Cell-Autonomous (Cell-Intrinsic) Stress Responses.- Regulated Cell Death.- Epilogue: The Horror of an Injury-Induced Avalanche of DAMPs.- Part VI. Innate Immune Effector Responses.- Prologue: The Various Facets of Innate Immune Effector Responses.- Cellular Inflammatory Responses.- Humoral Innate Immune Effector Responses.- Regulation of Innate Inflammatory Responses.- Epilogue to Part VI.- Part VII. Function of Innate Lymphoid Cells and Unconventional T Cells with Partial Innate Function.- Prologue: The "Ready-to-Go" Lymphocytes of the Immune System.- Activating and Function of Innate Lymphoid Cells.- Activating and Function of Unconventional T Cells.- Epilogue: Killer Lymphocytes as Tools for Future Immunotherapeutic Approaches.- Part VIII. DAMPs Promoting Adaptive Immunity and Tissue Repair.- Prologue: The "Long Arm" of DAMPs in Shaping Adaptive Immune Responses and Tissue Repairing Processes.- Antigen Uptake, Processing and Presentation by Dendritic Cells.- Antigen in the Presence of DAMPs Induces Immunostimulatory Dendritic Cells to Promote "Destructive" Acquired Immune Responses.- Antigen in the Absence of DAMPs Promotes Immunotolerance: the Role of Dendritic Cells and Regulatory T Cells.- An Impressive Example of Peripheral Tolerance against Nonself: Tolerance to Commensal Bacterial and Dietary Protein Antigens.- Immunometabolism of Dendritic Cells and T Cells.- Role of DAMPs in Tissue Regeneration and Repair.- Epilogue: DAMPs as Key Players in the Pathogenesis of Many Human Diseases.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
