DNA Replication
-15%
portes grátis
DNA Replication
From Old Principles to New Discoveries
Foiani, Marco; Masai, Hisao
Springer Verlag, Singapore
01/2018
581
Dura
Inglês
9789811069543
15 a 20 dias
1323
Descrição não disponível.
Preface.- Biography.- Chapter1. Historical Perspective of Eukaryotic DNA Replication.- Chapter2. Regulation of replication origins.- Chapter3. Molecular mechanism for chromatin regulation during MCM loading in mammalian cells.- Chapter4. Initiation of DNA replication at the chromosomal origin of E. coli, oriC.- Chapter5. Initiation of DNA replication in the archaea.- Chapter6. Mechanism of lagging strand DNA replication in eukaryotes.- Chapter7. Functions of multiple clamp and clamp-loader complexes in eukaryotic DNA replication.- Chapter8. Termination of eukaryotic replication forks.- Chapter9. Structure of the MCM2-7 double hexamer and its implications for the mechanistic functions of the Mcm2-7 complex.- Chapter10. Architecture of The Saccharomyces cerevisiae Replisome.- Chapter11. Replication domains: genome compartmentalization into functional replication units.- Chapter12. Rif1-dependent regulation of genome replication in mammals.- Chapter13. G-quadruplexes and DNA replication origins.- Chapter14. Interaction of Rif1 protein with G-quadruplex in control of chromosome transactions.- Chapter15. Chromatin replication and histone dynamics.- Chapter16. The temporal regulation of S phase proteins during G1.- Chapter17. Roles of SUMO in replication initiation, progression, and termination.- Chapter18. The multiple roles of ubiquitylation in regulating challenged DNA replication.- Chapter19. Regulation of mammalian DNA replication via the ubiquitin-proteasome system.- Chapter20. Coordinating replication with transcription.- Chapter21. Fragility extraordinaire: Unsolved mysteries of chromosome fragile sites.- Chapter22. Cyclin E deregulation and genomic instability.- Chapter23. Replication through repetitive DNA elements and their role in human diseases.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
Replication origins;DNA replication initiation factors: DnaA, ORC, MCM;Replication timing: TAD, LAD, and Rif1;Chromatin regulation of DNA replication;Structures of replication complexes: Cryoelectron microscopy;Ubiquitination and SUMOylation of replication factors;Replication/transcription collision;G-quadruplex and RNA-DNA hybrids;Replication fork factors;Chromosomal fragile sites;Clamp loaders;Repetitive DNA elements;Genome instability;DNA polymerases;FEN1;cytogenetics
Preface.- Biography.- Chapter1. Historical Perspective of Eukaryotic DNA Replication.- Chapter2. Regulation of replication origins.- Chapter3. Molecular mechanism for chromatin regulation during MCM loading in mammalian cells.- Chapter4. Initiation of DNA replication at the chromosomal origin of E. coli, oriC.- Chapter5. Initiation of DNA replication in the archaea.- Chapter6. Mechanism of lagging strand DNA replication in eukaryotes.- Chapter7. Functions of multiple clamp and clamp-loader complexes in eukaryotic DNA replication.- Chapter8. Termination of eukaryotic replication forks.- Chapter9. Structure of the MCM2-7 double hexamer and its implications for the mechanistic functions of the Mcm2-7 complex.- Chapter10. Architecture of The Saccharomyces cerevisiae Replisome.- Chapter11. Replication domains: genome compartmentalization into functional replication units.- Chapter12. Rif1-dependent regulation of genome replication in mammals.- Chapter13. G-quadruplexes and DNA replication origins.- Chapter14. Interaction of Rif1 protein with G-quadruplex in control of chromosome transactions.- Chapter15. Chromatin replication and histone dynamics.- Chapter16. The temporal regulation of S phase proteins during G1.- Chapter17. Roles of SUMO in replication initiation, progression, and termination.- Chapter18. The multiple roles of ubiquitylation in regulating challenged DNA replication.- Chapter19. Regulation of mammalian DNA replication via the ubiquitin-proteasome system.- Chapter20. Coordinating replication with transcription.- Chapter21. Fragility extraordinaire: Unsolved mysteries of chromosome fragile sites.- Chapter22. Cyclin E deregulation and genomic instability.- Chapter23. Replication through repetitive DNA elements and their role in human diseases.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
Replication origins;DNA replication initiation factors: DnaA, ORC, MCM;Replication timing: TAD, LAD, and Rif1;Chromatin regulation of DNA replication;Structures of replication complexes: Cryoelectron microscopy;Ubiquitination and SUMOylation of replication factors;Replication/transcription collision;G-quadruplex and RNA-DNA hybrids;Replication fork factors;Chromosomal fragile sites;Clamp loaders;Repetitive DNA elements;Genome instability;DNA polymerases;FEN1;cytogenetics
