Bacteriophages

Bacteriophages

Biology, Technology, Therapy

Burrowes, Benjamin H.; Abedon, Stephen T.; Harper, David R.; McConville, Malcolm L.

Springer International Publishing AG

1206

Inglês

9783319419879

Descrição não disponível.
1 Bacteriophage Biology



1. Structure and function of bacteriophages



2. Bacteriophage infection and lysis



3. Lysogeny



4. Transduction



5. Genetics and genomics of bacteriophages

6. Bacteriophage discovery and genomics

7. Host resistance and bacteriophage counter-resistance

8. Bacteriophage ecology, population biology and biotechnology

9. Bacteriophage pharmacology and immunology

10. Bacteriophage as biocontrol agents




2 History of Bacteriophages



1. The discovery of bacteriophages and the historical context



2. Early therapeutic and other uses of bacteriophages

3. Interregnum and renaissance of bacteriophages








3 Bacteriophage Technology



1. Isolation of bacteriophages



2. Bacteriophage use in molecular biology and biotechnology



3. Detection of bacteriophage: Plaques and plaque assay



4. Detection of bacteriophage: Statistical asoects of plaque assay



5. Detection of bacteriophage: Electron microscopy and visualisation



6. Detection of bacteriophage: Sequence-based systems

7. Detection of bacteriophages: Mass spectroscopy and novel approaches

8. Use of bacteriophages as detection agents

9. Phages in nanotechnology: History and future

10. Intellectual property issues for bacteriophages

11. Optimisation of host strains in bacteriophage production

12. Manufacture of bacteriophages







4 Agriculture, Food and Environmental Use of Bacteriophages



1. Environmental hygiene and bacteriophages



2. Industrial processes and biofilm applications of bacteriophages



3. Crop use of bacteriophages



4. Food safety and bacteriophages



5. Bacteriophage utilization in animal hygiene








5 Therapeutic use of Bacteriophages



1. Summary of current Eastern Europe phage use



2. The use of bacteriophages in veterinary therapy

3. GM and non-replicating bacteriophage



4. Enzybiotics: lysins and bacteriocins



5. Phage display



6. Phages as carriers



7. Regulatory aspects of bacteriophage therapy



8. Clinical trials of bacteriophage therapeutics
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Bacteriophages;Host resistance;Phage infection;Biocontrol agents;Environmental Hygiene;antibiotic resistance;gene therapy